Digital Business Solution Architect

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Position Summary:                    

We are looking for an experienced Business Solution Architect to drive the design and delivery of scalable, secure, and business-aligned solutions across our cloud ecosystem. This role bridges business strategy and technology execution, requiring deep technical proficiency in Angular, .NET Core, and NestJS, along with strong SQL and cloud platform experience.

You will work closely with stakeholders to understand business needs and translate them into effective architectural solutions. As a key technical leader, you will guide engineering teams, shape system architecture, and ensure our technology investments support long-term business success.

Position Responsibilities:

• Lead the design and architecture of cloud-native solutions that align with business objectives and user needs.

• Partner with business units, product managers, UX teams, and engineering to define end-to-end solutions that balance functionality, scalability, performance, and cost-effectiveness.

• Act as the architectural owner across application layers—UI, backend services, APIs, databases, and cloud infrastructure.

• Guide the integration of AI/ML, data engineering, and operational workflows into cohesive business solutions.

• Produce clear architectural documentation, solution proposals, and system blueprints to drive implementation.

• Uphold enterprise standards for security, performance, and maintainability.

• Provide leadership during system troubleshooting and contribute to incident resolution with a holistic architectural perspective.

• Support strategic planning, technical roadmaps, and continuous improvement initiatives in line with business growth.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Position Requirements:

• Proven experience aligning technical solutions with business strategies in a cross-functional environment.
• Ability to evaluate and recommend technologies that add business value and operational efficiency.
• Strong mentoring capabilities to upskill development teams and promote architectural best practices.
• Expertise in microservices, RESTful APIs, CI/CD, DevOps, and modern development frameworks.
• Deep hands-on experience with cloud platforms (Azure preferred), infrastructure design, and system integrations.
• Excellent problem-solving, documentation, and stakeholder communication skills.

All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodation for additional task and responsibilities.

Preferred Experience/Education/Skills:

• Bachelor’s or master’s degree in computer science, Engineering, or related discipline.
• 8+ years in project lifecycle, with at least 3 years focused on architecture or business solution design.
• Strong technical foundation in .NET Core, Angular, NestJS, and SQL.
• Experience with API data formats (XML/JSON), Git version control, and database design/optimization.
• Familiarity with data architecture, quality, and governance best practices.
• Understanding of full SDLC, including testing, operations, and continuous delivery pipelines.
• Relevant certifications (e.g., Azure Solutions Architect Expert, AWS) are a plus.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact View email address on swooped.co. To learn more, visit: The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.